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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a0b627cdcc30b306872cf5f82df1451f9ae336ec6de26ef835ead09a5be0b35' 
  AND token = 'sBc6VTGEqb6QGLjoA+BCaiYkK+JQKk3oNcsPZGP5mIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}