SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd827f9e458ab9904564c73b5d13671cf8b6bab9558bb6d44fc4b4667378026da' 
  AND token = 'LVLzGwM+SPNkuf0eNFo/isZbocLcWJpolRR5P1tMk4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}