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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b889759b2a903ca0ca9a561c51f566a8b7e5853349be469417447389d059c443' 
  AND token = 'DEVGE5iYR0x4jAEq7tL6K9t7Y8yBUTQRs3ueisK42+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}