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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e759898a09623e1f9b2bae3c838d25ed2ba57f4acfbdac2b02454190c9c92740' 
  AND token = 'wV/tAsV6lFthAFA9AR41/AcBj09GoPBJ+JD7V1qGrAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}