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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3503b21e6e7a60dae56fa74afca7125a4c8c1c7823a89eab83a27f1d2572df76' 
  AND token = 'HJu6NlLEd0Py43KJKHFU571Nj6qjkPdCSUFVfY6A8SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}