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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34ab4505435b06abf7fe9c14ddb3a22193a1fa376010e27767e70c09fc398489' 
  AND token = 'mc5nQC4PTKlUjsGJMym4MrE1slr5eotvwLjjXpeITdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}