SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9ffbeeb4ab23dd825e89369372d5da6f729cfa229374321007e5d390f737fe0' 
  AND token = 'PoKRL21qPCf2VYJ2SCF5m9Vr2z+utvgZICvyCP6vAug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}