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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6359f3df773a0479070c44f9951548ac751e4db468c41c3d188ecffff9ebf8a' 
  AND token = '1ZHDEBRtInZb91T+m2r8n0v892fTwMPya9JBWGzUVpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}