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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fc9770b8f105e30ea39a916e553e94e40af718e1868ed3de50d70ea90be95f0' 
  AND token = 'aopx6FVAo/+nVeJBq3Kqt/dc+yI5uTiIvvzqaRzbYT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}