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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354349f58b91c3ec3a30119e92e8c8a95152cbcb41abe9ecdb1f7e080e3c6b6b' 
  AND token = 'rkrNOci9Y/9K7HaGGWOi0TqhxKYxD4pioN4jmjXobec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}