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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110b5d4e93bb347ab5283e3eaa87e8fcfc1644afc035b505f37b9634bedf3b18' 
  AND token = 'Jq05amCpAm6NjHCqbQ63WXHKJ0lRtLQ6i4YIowVtVeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}