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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26c6b6419f0560f7319f3b234aa14cb879fa5456d6216804d7c6d4053c149518' 
  AND token = 'TBl8Mm+wunT4+6xLEiFxhYkDJPFYPfh0YdxaI4e8qjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}