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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7762baa935522320f72f038d72832d8c71371a446ac0f2170ddd4f0466b8ced' 
  AND token = 'DOy0O5RFOvXNcf7/wNTwyFsuePBmsRkY5D3Z93oU9rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}