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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4121a426045ccdb1abe2c07319f84cc6b9dca576ebaf752d5f5c0f78b2f7e24' 
  AND token = 'MWV93VenKngk2RSRzdVPvpfznsdC6shb28qb8kr/zfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}