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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21b2642ca6702715a8503dd84a2dc682fa62fac6e9a907c827611329eb4685e' 
  AND token = 'DQthOjwx5d+0u1g8xA1p7m12cEPcELpG/d8zPtBX+gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}