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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d1f2781001d4207fc1609c9f13ae619de2b1f8ab334feb56fc2cee28ef1110' 
  AND token = 'V/+NMWM6JPjSp3/FlbYikiYBYS1z6EJnPOZJ3UotP6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}