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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48504571809da64e2a4e697310f677ae12b127d500ad0d73994fdf259b9dcaed' 
  AND token = 'AcLJow0iAyw+gkRlcKvLKtVzS8wMbASx724f2ihRtaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}