SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddf02cbd5f2e37abe3b2256c41d9a96368437f32600be8e020b02cc34dbc1a05' 
  AND token = 'cFxpanFRcFP4AJ7MaVaufEO9JS/tsJUQlbJ80Zi5ZIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}