SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15de3aec5ebc2e03fa4c847370351fd0c145cba32ee20644f58145794bddc031' 
  AND token = 'ZJ+fwFgLkVaQ66L1UQF3rypIobvSkhcl7yXM2JrsAOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}