SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1244b6fbfa48c46e7522160ba521b130c3f27908d555df399821ed61254649' 
  AND token = 'Hol+2p8pqYMLwbNDvoglQJ8U7TRnbSw3NvjpYtGG2cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}