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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2269a8d8d1c077fd1da6b2969b946e0c48420cec87a71606fbea5dec3a285ec9' 
  AND token = 'GYi/ws6m6zU1Zg6AKNkX8k6rEEklyi4g8z/Q/Eb5QTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}