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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69274f30cce5de0b2050bf7a14d613e310a8f5d8593eb8774fd67047ad6ad1e6' 
  AND token = 'Qd2DuWteS2mre3MLez7SOCN+QJrB3fKuBQ6hBgXTLL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}