SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0e13b1e5ade028dc0078bb5ada33905a51bb51fe57b9359a5bad5c98ede470' 
  AND token = '2TBTN0H4IwpABTnTjHK+fcA/ZVs0Rkgus6fYHvzeVE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}