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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4434d0616d7d3c5e0175e56bc9cc49fe84171aa479c4783320ec14ef10b67413' 
  AND token = 'EtKzPzDiC2iLC8eXjoPf5fvpoe/9wa9ImOuuDlGQCNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}