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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c37d17f2c88f297d416e54d7b7a13867343e4fda1eb00105753fc49a0d04344' 
  AND token = 'az4Q/2Km1z2NYvNhLgXaM2/5f1Yu91aJPevlKeF9A9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}