SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331357001a029231c0b8a5a5951998431ef802e2047e19bbf5f159390a10c78c' 
  AND token = 'ID5D2eLK4HIkpHfZ7IYkC/2VJiXp8rkp74eRP27oGBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}