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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d06941f39487ba1e4f3b970a1073c4235aafc321e90cde15158b185f9c6b46' 
  AND token = '/02jfZIf8b7bH6m27cBzvcbaRt+v+4oV2nQnZcFgBWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}