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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a434ab43ea598673149437155df3fbeeb9b2bc41af31407a37959a758d02b59c' 
  AND token = 'GJvU8WN6EtMxeh1Nk28xGlFeF08orHzuRkYw0B07OKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}