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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5a2b73455b2f34da8befa72c9b1178dbc44fe209cdb7c09b0d96ad1c28943c' 
  AND token = 't6vlSghSAXc1bucCiPev8F5teA0c6gV9bMlg28IJbv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}