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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd67e6b3fde8d337d56b2f4d049c63a366f0b50c61758c8f0e7ce637e98be133' 
  AND token = 'nOkGQrWG40F42JFFmwo7VdDTj9UQMArU/py4/Eo6SV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}