SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a6f71a2d0db8736a30d0882ef578933a5e8094b0c1e99f9827137f371edc6f' 
  AND token = 'nF8viSpgnKpY7m0QZjgLcrvio0D9V/Z/tkyE1Hee67s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}