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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f5ffa1e088213f8209babd08497b3df5b8031ee410cf233fc1ed17b658a150' 
  AND token = 't/VPv5RI1sr2vQmnar618i+YuurmVSLirdvScsG599k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}