SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0bc485e45c6d5174f9d6b246c2b3727722e0ceed6d8209b3ade44b649d42e33' 
  AND token = 'yRGmXktazWZCo9ZX159QmYxvIOYDzTKG1NZVTFW7vAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}