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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80adfea11f0d96e427a3031c0f0319b037d5be01aeeb49356672bc0f36e5aa55' 
  AND token = 'S1ubwDWwtO1Uwq+mm+2AlaqD+L3DGhReQB8upicWlsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}