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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd64ee16ee0d1a7367f0206616fd2c6deb9e630d787f720d71d6bd22ec3636230' 
  AND token = 'lsV2HzzIf55d+q+ZyZpSJ1/u715Gka+wKOErfvEaxug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}