SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bfcc48c6a14caf0c0922150f20f8ab8936cc35b7e20a985ac9703787630bd03' 
  AND token = '0MJ7jgjuZyKL8UHmC51eZar/zsjqW9B3vJ0uLveJ0kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}