SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7c86a01449f86b39a7391b1d145292a9665d2d38b9cc3d12625ecbb84a0ad3' 
  AND token = 'gGPRP0VUsRAchnFR9P/p2IRcKGbj5PsHcUlKXCcHOhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}