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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b39a92e9bd3a04d7da33e39950408a7a60ef544a3a21f03960e025acc54446' 
  AND token = 'jZpyOAof3TEBOcZHByFL8pYI8W9rYXkMdi4HTdcFtps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}