SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a0ef121d36dd6755b4ad274c0ff753ba21d7981ae076a2433b1be521dbfb6a' 
  AND token = '7M8ZGt9eKETUDWq9wscG44aTUmxQSA6QRVN8laHh1lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}