SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2cb6161782dd8b08c243eb383430342bf705f13ec4e852370c2632f2ebf729' 
  AND token = 'bpSZGFquJ/NrxhS8vcVjwlg5TLKtF2r1ejKPz9KOeqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}