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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765854328d792474f73f12d8a3124d496a914ffc014b129b1f14a0776a477739' 
  AND token = 'yYBxAoBnYQYfGTRtvRanE+DEE8ebB4+D0gKARi3KnWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}