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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee27740a836e54b5e06b0da6e6cf982b28f37432e549012a833826e210d9d4cd' 
  AND token = 'wGJD5ujeZn3IyzTTgb6hUTtyhuBuqLiISQTtw0KuLb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}