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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83e7648a875d535f478c6e9e17d8723784519576141402910226509698cc7e3c' 
  AND token = 'PVA0w8wqCiktLciOH9lcA+EY5/k06h/qm527DiiW53g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}