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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e357842ee1ea64ab42876c1bc44d58ba955fbb108e6645c8dd9db5bbe9c3014d' 
  AND token = 'I5VFttCipitIDiwtZToSQrhfQZ3TU5aPDWK2gPC2QTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}