SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '526fa3e3ef68fa8bd956fac86e06ae25e9a7ec08ffbc098085af5ada977faf8b' 
  AND token = '3eQSOyMhR9Xj1OsqufLWP+qMnxYAZ6xue2p1IwMQeWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}