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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9097d50380fe4dc37d4bd240310181ec79e3bbf3bed7bf6340eba93a90e32b31' 
  AND token = 'QTsLc38MD/O+E78jlOz/ghbspgbJzX8RbeJJQ2pfJtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}