SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c35a5b50d5b8edbc1878b3cb74c62890357def45d7c03ca87038a9db0169d3e' 
  AND token = 'GVI8F9HbSSrYFzmxIwaTad0iC8+1WBG+VvmjzSIMB3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}