SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208e0f7213341a48a88cd8e577f316e5b66c7c8313e4d6b79cf8d3984c1fb945' 
  AND token = 'M4/hhIvr8xEt16Dxl8OqcsDSWtHM6yiOAB3fbvp9AAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}