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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e22f5a3e152a1d86c59fa6569ac77cc142a64a90507c8ffbad5f3d3e55821e6' 
  AND token = 'DL73jmNpcI4XLy9gfGsXVI3U8ZagfoB3+ilDw01jyA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}