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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a8485fc7ed299c50251ff7a85d73aca106284d32c8f63133de3709aa4ca3a0' 
  AND token = 'J2M1kr/BXA2kHIveQp2TlrIHyARG96Ru8ZOQ+PEIYMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}